Denali Therapeutics Inc.

Denali Therapeutics Inc.verified

DNLI

Price:

$20.92

Market Cap:

$3.01B

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutic candidates for neurodegenerative diseases in the United States. It offers leucine-rich repeat kinase 2 (LRRK2) inhibitor product candidate, including BIIB122/DNL151, a small molecule inhibitor, which is in phase I and phase Ib clinical trials for the treatment of Parkinson's disease. The company also develops DNL310 that is in Phase I/II clinical trials for the treatment of hunter syndrome; DNL343, which is in phase 1 clinical trial the treatment of amyotrophic lateral sclerosis (ALS); AR443820/DNL788 completed a phase I clinical trial for the treatment of ALS, multiple sclerosis (MS), and Alzheimer's d...[Read more]

Industry

Biotechnology

IPO Date

2017-12-08

Stock Exchange

NASDAQ

Ticker

DNLI

The ROE as of December 2024 (TTM) for Denali Therapeutics Inc. (DNLI) is -32.93%

According to Denali Therapeutics Inc.’s latest financial reports and current stock price. The company's current ROE is -32.93%. This represents a change of 289.16% compared to the average of -8.46% of the last 4 quarters.

Denali Therapeutics Inc. (DNLI) Historical ROE (quarterly & annually)

How has DNLI ROE performed in the past?

The mean historical ROE of Denali Therapeutics Inc. over the last ten years is -7.96%. The current -32.93% ROE has changed 313.76% with respect to the historical average. Over the past ten years (40 quarters), DNLI's ROE was at its highest in in the December 2020 quarter at 21.28%. The ROE was at its lowest in in the December 2019 quarter at -13.68%.

Quarterly (TTM)
Annual

Average

-7.96%

Median

-18.93%

Minimum

-50.04%

Maximum

107.38%

Denali Therapeutics Inc. (DNLI) ROE by Quarter and Year

Discovering the peaks and valleys of Denali Therapeutics Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 655.12%

Maximum Annual ROE = 107.38%

Minimum Annual Increase = -588.39%

Minimum Annual ROE = -50.04%

Quarterly (TTM)
Annual
YearROEChange
2023-14.09%-54.96%
2022-31.27%3.56%
2021-30.20%-588.39%
20206.18%-112.36%
2019-50.04%655.12%
2018-6.63%-65.00%
2017-18.93%-44.39%
2016-34.05%-131.71%

Denali Therapeutics Inc. (DNLI) Average ROE

How has DNLI ROE performed in the past?

The current ROE of Denali Therapeutics Inc. (DNLI) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-25.19%

5-year avg

-23.88%

10-year avg

-7.96%

Denali Therapeutics Inc. (DNLI) ROE vs. Peers

How is DNLI’s ROE compared to its peers?

Denali Therapeutics Inc.’s ROE is greater than Homology Medicines, Inc. (-100.91%), greater than Stoke Therapeutics, Inc. (-54.45%), greater than Atreca, Inc. (-199.88%), greater than Black Diamond Therapeutics, Inc. (-68.08%), greater than 4D Molecular Therapeutics, Inc. (-28.00%), less than Ascendis Pharma A/S (212.63%), greater than Apellis Pharmaceuticals, Inc. (-103.92%), greater than BeiGene, Ltd. (-25.12%), greater than Akero Therapeutics, Inc. (-32.52%), greater than Blueprint Medicines Corporation (-47.66%), greater than Legend Biotech Corporation (-29.69%), greater than Vaxcyte, Inc. (-23.53%), greater than Travere Therapeutics, Inc. (-541.59%), greater than Cerevel Therapeutics Holdings, Inc. (-98.94%), greater than Avidity Biosciences, Inc. (-27.66%), greater than Revolution Medicines, Inc. (-33.67%), greater than Day One Biopharmaceuticals, Inc. (-22.40%), greater than SpringWorks Therapeutics, Inc. (-48.21%), greater than Monte Rosa Therapeutics, Inc. (-62.68%), greater than Design Therapeutics, Inc. (-18.01%), greater than Werewolf Therapeutics, Inc. (-58.83%), greater than Ikena Oncology, Inc. (-39.59%),

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