Aeglea BioTherapeutics, Inc.

Aeglea BioTherapeutics, Inc.verified

AGLE

Price:

$12.01

Market Cap:

$1.37B

Aeglea BioTherapeutics, Inc., a clinical-stage biotechnology company, designs and develops human enzyme therapeutics for the treatment of patients and families with rare metabolic diseases. The company's lead product candidate is pegzilarginase, a recombinant human Arginase 1 that is in Phase III PEACE trial to evaluate the safety and efficacy for the treatment of Arginase 1 deficiency. It also develops AGLE-177, a polyethylene glycol modified, which is in Phase I/II clinical trial for the treatment of patient with homocystinuria. In addition, the company's preclinical pipeline includes AGLE-325 for the treatment of cystinuria, as well as other research programs. The company was formerly kno...[Read more]

Industry

Biotechnology

IPO Date

2016-04-07

Stock Exchange

NASDAQ

Ticker

AGLE

The ROE as of December 2024 (TTM) for Aeglea BioTherapeutics, Inc. (AGLE) is -82.81%

According to Aeglea BioTherapeutics, Inc.’s latest financial reports and current stock price. The company's current ROE is -82.81%. This represents a change of 250.17% compared to the average of -23.65% of the last 4 quarters.

Aeglea BioTherapeutics, Inc. (AGLE) Historical ROE (quarterly & annually)

How has AGLE ROE performed in the past?

The mean historical ROE of Aeglea BioTherapeutics, Inc. over the last ten years is -135.56%. The current -82.81% ROE has changed -38.91% with respect to the historical average. Over the past ten years (40 quarters), AGLE's ROE was at its highest in in the June 2023 quarter at 104.68%. The ROE was at its lowest in in the December 2014 quarter at -169.93%.

Quarterly (TTM)
Annual

Average

-135.56%

Median

-72.08%

Minimum

-552.72%

Maximum

-31.28%

Aeglea BioTherapeutics, Inc. (AGLE) ROE by Quarter and Year

Discovering the peaks and valleys of Aeglea BioTherapeutics, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 112.55%

Maximum Annual ROE = -31.28%

Minimum Annual Increase = -Infinity%

Minimum Annual ROE = -552.72%

Quarterly (TTM)
Annual
YearROEChange
2023-184.11%10.50%
2022-166.61%112.55%
2021-78.39%35.50%
2020-57.85%-55.58%
2019-130.25%98.03%
2018-65.77%21.56%
2017-54.11%57.02%
2016-34.46%10.15%
2015-31.28%-94.34%
2014-552.72%-Infinity%

Aeglea BioTherapeutics, Inc. (AGLE) Average ROE

How has AGLE ROE performed in the past?

The current ROE of Aeglea BioTherapeutics, Inc. (AGLE) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-143.04%

5-year avg

-123.44%

10-year avg

-135.56%

Aeglea BioTherapeutics, Inc. (AGLE) ROE vs. Peers

How is AGLE’s ROE compared to its peers?

Aeglea BioTherapeutics, Inc.’s ROE is greater than Edgewise Therapeutics, Inc. (-26.83%), greater than Ikena Oncology, Inc. (-39.59%), greater than Design Therapeutics, Inc. (-18.01%), greater than Xilio Therapeutics, Inc. (-214.74%), less than Eliem Therapeutics, Inc. (0%), less than eFFECTOR Therapeutics, Inc. (2.18%), greater than Landos Biopharma, Inc. (-73.00%), less than Apexigen, Inc. (48.27%), greater than Navidea Biopharmaceuticals, Inc. (-173.56%), greater than Angion Biomedica Corp. (-98.89%), greater than SAB Biotherapeutics, Inc. (-94.37%), greater than Senti Biosciences, Inc. (-154.84%), greater than Cingulate Inc. (-113174.53%), less than Bellicum Pharmaceuticals, Inc. (33.22%), greater than Hillstream BioPharma, Inc. (-172.28%), greater than Neoleukin Therapeutics, Inc. (-8.54%), greater than CytomX Therapeutics, Inc. (-41.34%), greater than Assembly Biosciences, Inc. (-121.46%), greater than Instil Bio, Inc. (-37.44%), greater than Nuvation Bio Inc. (-108.68%), greater than Applied Molecular Transport Inc. (-131.59%), greater than Catalyst Biosciences, Inc. (-63.14%), greater than Aileron Therapeutics, Inc. (-46.89%), less than Bio-Path Holdings, Inc. (2.62%), greater than Benitec Biopharma Inc. (-60.28%),

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